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Notes from building an AI co-scientist.
Research, method and engineering writing from the team building the co-scientist.
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Releases, milestones and announcements.
ProductSep 11, 2026
Early access to Helixir opens to research teams
Research and biotech teams can apply for early access to the Co-Scientist and run hypothesis discovery, de novo design and literature review on their own targets.
ResearchSep 6, 2026
MIRAGE: a benchmark for protein-family generalization in affinity prediction
Our preprint treats historical public protein-family support as an explicit experimental variable, for affinity and for pose, and reports what happens to frontier co-folders on families they have not seen.
ResearchSep 1, 2026
OIL: an open codon-resolved nucleotide framework, presented at MoML 2026
The Omics Integrated Library assembles 2.35 trillion nucleotides across fifteen sources, codon-resolved and with provenance on every record. Scripts and the automated procedure follow later this year.
ResearchDec 1, 2025
First equivariant foundation model for mRNA design at NeurIPS 2025
Our foundation model learns biology in a geometry-aware representation: the technical core the co-scientist platform is built on.
ResearchAug 21, 2025
Equi-mRNA: the first codon-level equivariant mRNA language model
Our paper encodes synonymous-codon symmetry directly into the representation as SO(2) cyclic subgroups, rather than leaving a language model to infer it from data.
Most read
01Codon resolution at metagenomic scale: why we built OILResearch · 5 min02Codon-level equivariance: what it fixes, and what it does notResearch · 2 min03Introducing Equi-mRNA: the first codon-level equivariant mRNA language modelResearch · 8 min04What we keep in the knowledge graph, including the things that did not workEngineering · 2 min
